FOR CHRONIC MIGRAINE THAT HASN’T RESPONDED TO MEDICATION

A Drug-Free, Minimally Invasive Migraine Procedure

TEMMA® gently seals a tiny artery linked to migraine pain — performed by the fellowship-trained neurointerventional specialists of Cortex Migraine. No brain surgery. You go home the same day.

Take the 5-Minute QuestionnaireHow TEMMA Works

Performed by fellowship-trained neurointerventional specialists — a multi-physician group, focused on one thing.

Prefer to talk to a real person? Call (833) 426-7839
The Practice Behind Your Care

A new treatment model — interventional migraine care.

Cortex Migraine is a physician-led, multi-state interventional migraine group with locations across the Western U.S. — fellowship-trained neurointerventional specialists, certified to perform the TEMMA® procedure, with one standardized, thoroughly vetted protocol — delivered the same way at every clinic.

Interventional migraine care: the TEMMA® procedure and the predictive lidocaine test.

Cortex Tacoma — openCortex Olympia — openCortex Los Angeles — openMore clinics coming soon
Our locations →Meet our providers →
10,000+ performed worldwide40-minute procedureSame-day dischargeMRI-safe coils
The Science

What Is TEMMA®?

TEMMA® (Targeted Embolization for Migraine Management) is a minimally invasive treatment that uses a tiny soft coil to gently seal the middle meningeal artery (MMA) — a vessel linked to migraine-generating pain pathways. Many migraines begin in the dura — the pain-sensitive layer inside the skull — which this artery supplies.

Microcatheter guided into the artery
1
A microcatheter is guided to the artery through a tiny wrist or groin access.
Soft coil deploying from the catheter
2
A tiny soft coil is deployed — it forms gently inside the artery.
Artery sealed by the coil
3
The artery is sealed, quieting the migraine-related pain pathway.
How the procedure works →See the published evidence →
Published Research

The Evidence

Zero
Serious complications across all published studies
~90%
Of patients report improvement in published series
30.5
Average HIT-6 improvement, sustained at 6 months

Studies consistently show no loss of brain function, no cognitive changes, and extremely low rates of serious complications.

Read the published research →Full safety profile →

Candidacy

TEMMA® May Be Right For You If…

  • Severe migraine — 8 or more headache days a month
  • Migraines that don't improve with medication
  • Tried CGRP inhibitors, Botox, or other preventives without enough relief
  • Side effects from your current treatments
  • Wanting a drug-free, minimally invasive option

Not sure? The free questionnaire is the fastest way to find out — reviewed by our specialists, with clear next steps either way.

See If You May Qualify

See the full candidacy criteria →

Questions Patients Ask

Straight answers

Take the first step.

It’s free, it takes 5 minutes, and an interventional migraine specialist reviews your answers — with clear next steps: a consultation, or a different treatment path.

Get StartedOr call (833) 426-7839

We work with your insurance to cover most or all of the process — and handle the legwork for you.

HIPAA-compliant — your information stays privateText Messaging Consent. You consent to communication via text message.

Check Candidacy